The Effect of Low-Dose Naltrexone on Medication in Inflammatory Bowel Disease: A Quasi Experimental Before-and-After Prescription Database Study.

J Crohns Colitis · 2018 · PMC5972567 · PMID 29385430

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did not reach statistical significanceno p-value reported

There was a striking 111% relative increase in the dispensing of TNF-α inhibitors in the UC LDN ×1 group that coincided with the initiation of LDN [see figures in Supplementary data 6 and 7 ], but this did not reach statistical significance.

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