Germline genetic testing in prostate cancer - further enrichment in variant histologies?

Oncoscience · 2018 · PMC5978447 · PMID 29854870

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a strong trendno p-value reported

In the previously mentioned retrospective study by Mateo et al , use of a PARP inhibitor or platinum-based chemotherapy resulted in an overall survival hazard ratio of 0.59 (95% CI 0.28-1.25; p=0.17), a strong trend towards an improved outcome.

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