did not reach statistical significancep = 0.0632
Sham + P70 mice with a fracture showed significantly higher Iba-1 in the ipsilateral cortex and hippocampus compared to their respective contralateral regions ( t -tests, p < 0.0001), whereas Sham + P70 mice without a fracture did not reach statistical significance ( t -test, p = 0.0632 and 0.0951, for cortex and hippocampus, respectively).