ADAR1-mediated regulation of melanoma invasion.

Remarkably, analysis of ITGB3 and ADAR1 expression levels in 38 low-passage patient-derived metastatic melanoma cultures shows a highly significant negative correlation (Fig. 2a ).

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While PAX6 was congruently increased in some patients, it did not reach statistical significance (Fig. 5i, j , Supplementary Fig. 6 ).

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