Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs.

For menstrual fever (QOL impact), we observed a nominally significant association signal at chr6:154.33–154.46 Mb (top SNP: rs17181171; P = 1.98 × 10 −8 ) that overlaps over half of the 5′-end of the opioid receptor mu 1 ( OPRM1 ) gene (Fig. 5a ) and contains 65 high LD SNPs (Supplementary Worksheet S6).

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