Sex differences in outcomes of primary prevention implantable cardioverter-defibrillator therapy: combined registry data from eleven European countries.

Data from the primary prevention ICD patients with ischaemic heart disease enrolled in the Danish ICD registry also showed a trend towards higher mortality in men. 23 In patients with non-ischaemic cardiomyopathy, however, there was no difference in mortality. 16 In contrast to our results, the French DAI-PP registry only showed a lower mortality in women receiving a CRT-D (HR 0.68; P = 0.034) but no significant lower mortality of women in the overall primary prevention ICD cohort (HR 0.87; P = 0.32). 17 This difference to our findings can in part be explained by the fact that 61% of women in the French study but only 51% in our study received a CRT-D.

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