NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity.

Under unstimulated conditions, GFP‐S387D‐Ago2 showed a dramatic increase in binding to endogenous GW182 compared to GFP‐WT‐Ago2, while GFP‐S387A‐Ago2 bound GW182 slightly less than WT, which did not reach statistical significance (Fig 3 A).

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