The co-existence of NS5A and NS5B resistance-associated substitutions is associated with virologic failure in Hepatitis C Virus genotype 1 patients treated with sofosbuvir and ledipasvir.

PLoS One · 2018 · PMC5983500 · PMID 29856885

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did not reach statistical significanceno p-value reported

In the present study, most patients with a single RAS of NS5A were achieved an SVR; however the result did not reach statistical significance, because of the small number of cases.

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