In agreement with the transcriptional findings, the expression of SIRT6 in adipose tissue showed an increasing trend when T1AM was used at the highest dose, however, this trend did not reach statistical significance and it is not reported in Figure 6 . 2.5.
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Metabolic Reprogramming by 3-Iodothyronamine (T1AM): A New Perspective to Reverse Obesity through Co-Regulation of Sirtuin 4 and 6 Expression.
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