nominally significantP =0.0061
Unlike singleton disruptive variants, although the burden of rare disruptive variants in SCZ was nominally significant, and survived FWER correction for all tests within the trait, it did not meet the threshold for tests across all traits (unadjusted P =0.0061, FWER within P =0.0228, FWER across P =0.0863, Supplementary Table S9 ).