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Gender Dependency in Streoselective Pharmacokinetics of Tramadol and Its Phase I Metabolites in Relation to CYP2D6 Phenotype in Iranian Population.

Iran J Pharm Res · 2018 · PMC5985193 · PMID 29881433

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A trend towards higher Vd/F values for EMs than PMs, especially for (+)-enantiomer was observed, however, the differences did not reach statistical significance when two phenotypic subgroups were compared.

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