Lipoprotein subclass concentrations showed a trend where the largest VLDL particles displayed the most pronounced associations that got weaker while the particle size decreased, and again stronger for medium and small LDL particles ( Fig. 1 , panel 1).
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NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects.
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