Endogenous glucagon-like peptide- 1 and 2 are essential for regeneration after acute intestinal injury in mice.

Co-treatment also tended to prevent the increase in mucositis severity score; however, this did not reach statistical significance ( Fig 3 ).

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When comparing aGLP-2 treatment with co-treatment we found that co-treatment prevented the BW loss from day 2 (this was highly significant during aGLP-2 treatment alone) and that SI weight and villus height in jejunum were significantly larger in co-treated compared to aGLP-2 treated animals.

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