In Vivo Optical Imaging of Myelination Events in a Myelin Basic Protein Promoter-Driven Luciferase Transgenic Mouse Model.

There was a dramatic decrease in luciferase activity in the brain of curpizone-demyelinated mice by Day 7, which was maintained at low levels after 28 days on the cuprizone diet ( p < .0001 for all time points) and showed a trend toward recovery by 35 days ( Figure 5(a) and (b) ).

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