Heterogeneous MYCN amplification in neuroblastoma: a SIOP Europe Neuroblastoma Study.

For stage 4, the outcome differed as well but did not reach statistical significance, possibly due to the rather small patient number (5-year EFS: <18 months: 0.76 ± 0.15; >18 months: 0.30 ± 0.09; p = 0.071; 5-year OS: <18 months: 0.76 ± 0.15; >18 months: 0.28 ± 0.09; p = 0.084 (Table 1 and Fig. 2 ).

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