Pneumococcal meningitis trends after pneumococcal conjugate vaccine introduction in Colombia: An interrupted time-series analysis.

Hum Vaccin Immunother · 2018 · PMC5989909 · PMID 29351491

Europe PMC DOI

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a significant trendno p-value reported

A significant trend towards reduced monthly was observed in the post-vaccination period (2012–2015) compared with the expected rate, reaching in 2015 a reduction of 90.5% of pneumococcal meningitis.

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an increasing trendno p-value reported

The results of our analysis indicate that the number of pneumococcal meningitis cases in Colombia showed an increasing trend until the year 2012.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.