The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells.

There was a trend toward fewer CXCR5 + IL-7R lo FOXP3 + CD4 + Tfr cells in the peripheral blood of tacrolimus treated patients both in proportion of CD4 + cells (Figure 4 E) and absolute cell count (Figure 4 F), but this did not reach statistical significance.

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