Barely Significant
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Membrane-bound estrogen receptor alpha initiated signaling is dynamin dependent in breast cancer cells.

Eur J Med Res · 2018 · PMC5992704 · PMID 29880033

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The expression change of CCND1 did not reach statistical significance similarly to the downregulated ERBB2.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.