CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease.

Mol Ther Nucleic Acids · 2018 · PMC5992788 · PMID 29858078

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did not reach statistical significanceno p-value reported

Also, the Aβ42 levels seemed to be decreased, although the differences did not reach statistical significance ( Figure 4 D).

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