MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of concept study for NIPT.

PLoS One · 2018 · PMC5995407 · PMID 29889893

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a clear trendno p-value reported

In addition, there was a clear trend in the scores’ increase with respect to the fetal fraction of the aneuploid samples.

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