Barely Significant
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Aflibercept in Diabetic Macular Oedema Previously Refractory to Standard Intravitreal Therapy: An Irish Retrospective Study.

Ophthalmol Ther · 2018 · PMC5997601 · PMID 29508370

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a significant trendno p-value reported
After 6 months of aflibercept, our cohort showed a significant trend towards reduction in injection frequency.

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borderline significantno p-value reported
Shah and Heier [ 12 ] found following a mean of 16 prior bevacizumab/ranibizumab injections borderline significant VA improvements and significant anatomical improvements after 2 months of aflibercept [ 12 ].

also in 11,409 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.