Statin dose reduction with complementary diet therapy: A pilot study of personalized medicine.

We observed that “R” exhibited higher concentration of HDL-C ( P = 0.031) and lower small HDL particle concentration ( P = 0.045) than “NR.” Although not significant, “R” showed a trend toward higher concentration of large HDL particles ( P = 0.063) and non-ABCA1 specific cholesterol efflux capacity ( P = 0.075) than “NR.” A positive linear correlation was observed between total CEC and HDL-C (r = 0.825; P = 0.003) and total HDL particle (r = 0.847; P = 0.002) for “R” ( Figure S5 ).

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