Ptges3 and Cbr1 were found to be significantly up-regulated in Cyp2j4 −/− macrophages ( Figure 5 D) whereas Cyp2j4 −/− SVF showed a trend for up-regulation of Ptgis after CAF ( Figure 5 E).
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Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis.
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