The EORTC 26981/22981-NCIC CE3 study excluded patients over 70 [ 1 , 2 ], and although a subgroup analysis showed a trend toward benefit in patients over 60 years old, the degree of benefit diminished with increasing age [ 19 ].
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The EORTC 26981/22981-NCIC CE3 study excluded patients over 70 [ 1 , 2 ], and although a subgroup analysis showed a trend toward benefit in patients over 60 years old, the degree of benefit diminished with increasing age [ 19 ].