A tutorial on conducting genome-wide association studies: Quality control and statistical analysis.

Int J Methods Psychiatr Res · 2018 · PMC6001694 · PMID 29484742

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nominally significantno p-value reported

For example, a PRS analysis of schizophrenia showed for the first time that an aggregate measure of the genetic risk to develop schizophrenia, estimated based on the effects of common SNPs (from the discovery sample) that showed nominally significant associations with disease risk, was significantly associated with schizophrenia risk in an independent (target) sample.

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