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Resveratrol Improves Muscle Atrophy by Modulating Mitochondrial Quality Control in STZ-Induced Diabetic Mice.

Mol Nutr Food Res · 2018 · PMC6001753 · PMID 29578301

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However, the level of PINK1 in the DM group was increased, but only partially attenuated with RSV, as these differences did not reach statistical significance (Figure 8 C). 4 Discussion In the present study, we demonstrated that RSV supplementation enhances muscle mass and improves physical activity by increasing mitochondrial content and suppressing the activation of the ubiquitin–proteasome system (UPS), autophagy, and apoptosis in DM mice.

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