ACRIN 6684: Multicenter, phase II assessment of tumor hypoxia in newly diagnosed glioblastoma using magnetic resonance spectroscopy.

PLoS One · 2018 · PMC6002091 · PMID 29902200

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showed a trendno p-value reported

In addition, Lac/Cr in tumor showed a trend towards association with OS-1, with higher Lac values predicting poorer outcome (AUC = 0.78, 95% CI: 0.49 to 1.00).

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