Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.

PLoS Med · 2018 · PMC6005466 · PMID 29912983

Europe PMC DOI

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did not reach statistical significanceP > 0.05actually significant

Following melatonin treatment ( n = 23), DLMO was advanced by 0.73 ± 1.21 h, compared to 0.24 ± 1.11 h following placebo ( n = 20) although this difference did not reach statistical significance ( P > 0.05).

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