Prescription opioid dispensing in New South Wales, Australia: spatial and temporal variation.

BMC Pharmacol Toxicol · 2018 · PMC6006696 · PMID 29914572

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a clear trendno p-value reported

Findings from the multivariable model suggest that age was a clear predictor of doses dispensed per person with a clear trend in increased doses with increasing age, peaking for those in the 65+ year age-group.

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a slightly increasing trendno p-value reported

Overall, there was a slightly increasing trend in the number of scripts written for, and persons prescribed, opioids between 2013 and 2015.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.