Efficacy and safety of sofosbuvir-based antiviral therapy to treat hepatitis C virus infection after kidney transplantation.

After stopping sofosbuvir and ribavirin, both tacrolimus and cyclosporine showed a trend toward an increase in C0 levels, but it was not statistically significant (C0 tacrolimus: 7.2 ± 0.51 ng/mL before stopping sofosbuvir, 5.6 ± 1.16 ng/mL on stopping sofosbuvir, 7.6 ± 3.5 ng/mL after stopping sofosbuvir; C0 cyclosporine: 83.6 ± 24.18 ng/mL before stopping sofosbuvir, 67.8 ± 30.4 ng/mL on stopping sofosbuvir, 75.6 ± 43.4 ng/mL after stopping sofosbuvir).

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