Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model.

EJNMMI Res · 2018 · PMC6008272 · PMID 29923139

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did not reach statistical significanceno p-value reported

The proliferation index of the combination-treated tumors was generally smaller than that of either single agent-treated tumors; a statistically significant difference was observed between the combination and 64 Cu-RaftRGD groups; however, the difference between the combination and 64 Cu-ATSM groups did not reach statistical significance.

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Uniform intratumoral distribution of radioactivity produced using two different radioagents, <sup>64</sup>Cu-cyclam-RAFT-c(-RGDfK-)<sub>4</sub> and <sup>64</sup>Cu-ATSM, improves therapeutic efficacy in a small animal tumor model.

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