Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes.

Of the 8 GWAS variants with p < 10 − 5 either tested in our eQTL mapping, or in high LD ( R 2 > 0.8 ) with a tested SNP, seven have a nominally significant marginal eQTL ( p < 0.05 , the 8th has p = 0.07 ) and four have a reQTL with p < 0.1 .

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