miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling.

Nat Commun · 2018 · PMC6010451 · PMID 29925839

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showed a trendP = 0.07so close (0.05 < p ≤ 0.1)

miR-143/145 +/− marrows also showed a trend toward reduced LT-HSC ( P = 0.07). miR-143/145 −/− and miR-143/145 +/− mice had similar marrow cellularity to WT mice suggesting a deficit in absolute number of HSC (Fig. 1b ).

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