Disease-specific regulation of gene expression in a comparative analysis of juvenile idiopathic arthritis and inflammatory bowel disease.

At an FDR of 10%, 34 of the 147 independent eQTL, highlighted in panel , show nominally significant interaction effects ( p < 0.02), implying different effect sizes in the two broad classes of disease.

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Individuals in each of the six health and disease categories are dispersed throughout the matrix but with highly significant tendencies for enrichment of specific expression clusters in each sub-type, as shown in Fig. 1 b.

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