Barely Significant
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Pressure Overload-induced Cardiac Hypertrophy Varies According to Different Ligation Needle Sizes and Body Weights in Mice.

Arq Bras Cardiol · 2018 · PMC6023638 · PMID 30226916

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showed a trendno p-value reported
At week 4 post-surgery, data ( Table 2 ) showed a trend of heart enlargement for mice with AAC, including thickening of the ventricular wall and an increase in chamber dilation; however, differences in EF and FS were not significant, indicating that changes in the heart structure did not have a pronounced effect on cardiac function at that time point.

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