Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting.

Mol Ther Nucleic Acids · 2018 · PMC6023838 · PMID 30195800

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

a positive trendno p-value reported

Monitoring rAAV6 transduction of HSPCs by qPCR of the vector genome relative to an albumin standard, we found no significant difference between plating conditions and number of vgs per cell over time; however, we did observe a positive trend in the number of vgs/cell with low-density culture conditions 8 and 24 hr post-transduction ( Figure 4 E).

also in 11,005 other papers

a clear trendno p-value reported

This demonstrated a clear trend between the expansion of cells in culture before gene targeting and the percentage of cells that underwent HR, which was CD34 + cell source (CB and PB) and donor independent.

also in 19,460 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.