CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.

Front Immunol · 2018 · PMC6024011 · PMID 29988398

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showed a trendno p-value reported

Stimulating B cells with R848 (TLR7/8 agonist) and IFNα showed a trend toward an increase in the percentage of CD19 + CD24 hi CD38 hi cells from CHC, but not in active on-treatment JDM patients [with PGA > 3.5 (range 0–10)] (Figures S5A,B in Supplementary Material).

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CD19<sup>+</sup>CD24<sup>hi</sup>CD38<sup>hi</sup> B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.

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