Histone Modulation Blocks Treg-Induced Foxp3 Binding to the IL-2 Promoter of Virus-Specific CD8⁺ T Cells from Feline Immunodeficiency Virus-Infected Cats.

Viruses · 2018 · PMC6024775 · PMID 29861472

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

Although the difference in Foxp3 binding to the IL-2 promoter between treated and untreated CD8 + T cells did not reach statistical significance ( p = 0.08), likely due to the low sample number, reduced Foxp3 binding was observed in each paired sample set, indicative of biological significance. 4.

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