Barely Significant
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Contact Allergy: A Review of Current Problems from a Clinical Perspective.

Int J Environ Res Public Health · 2018 · PMC6025382 · PMID 29844295

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a significant trendno p-value reported
For women, a significant trend was observed in terms of an increase in sensitization to FM I across the three decades.

also in 9,775 other papers

a decreasing trendno p-value reported
Of these, 2.5% were sensitised to diaminodiphenylmethane with a decreasing trend.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.