OCT1 haplotype (the four SNPs rs72552763, rs12208357, rs34130495, rs34059508) showed a trend with Ka, but problems occurred with the minimization and the Ka could not be estimated with adequate precision.
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Increased Metformin Clearance in Overweight and Obese Adolescents: A Pharmacokinetic Substudy of a Randomized Controlled Trial.
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