Enrichment of Clinically Relevant Organisms in Spontaneous Preterm-Delivered Placentas and Reagent Contamination across All Clinical Groups in a Large Pregnancy Cohort in the United Kingdom.

Although the majority of OTU and genus groupings did not reach statistical significance once adjusted for multiple testing ( Q > 0.1), some of the most significantly differentiated genera, such as Mycoplasma and Ureaplasma spp., were reported previously to be opportunistic intrauterine pathogens highly correlated with the incidence of sPTB ( 18 , 36 – 41 ), supporting the output from our study.

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