Avian Influenza Virus PB1 Gene in H3N2 Viruses Evolved in Humans To Reduce Interferon Inhibition by Skewing Codon Usage toward Interferon-Altered tRNA Pools.

mBio · 2018 · PMC6030557 · PMID 29970470

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a significant trendno p-value reported

A significant trend was not evident, and the PB1 mRNAs of early H3N2 viruses exhibit GC content that is still present in the PB1 mRNAs of the more recent H3N2 virus isolates, indicating that GC content does not drive the changes in the observed CAI values.

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