Inhibition of protein arginine methyltransferase 3 activity selectively impairs liver X receptor-driven transcription of hepatic lipogenic genes in vivo.

A highly significant positive correlation between FAS expression and SCD‐1 expression and between ACC expression and SCD‐1 expression was observed (Figure 3 C).

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Although the effects on ACC and SCD‐1 expression just failed to reach significance, a similar change in expression was observed compared with the expression pattern of FAS (Figure 3 B).

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LXRα gene expression levels showed a trend towards increase in the SGC707‐treated mice as compared with the other groups; however, this failed to reach significance (Figure 2 A).

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