Another SNP, rs16984571 located in KCNS3 intron, showed effect in the same direction as in GENRES in both replication cohorts, but the associations did not reach statistical significance.
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Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients.
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The sentences
BP levels were not included as covariates (although highly significant) as we presumed the effect of the genotypes to be principally mediated through BP levels.