Although the Swedish and Danish authors reported a decrease in utilities by 4% when severe actinic damage or previous SCC was present, this difference failed to reach statistical significance. 48 Moreover, the authors did not include patients with SCC, BCC and multiple diagnoses and could thus not assess the potential impact of disease progression. 48 On the other hand, the key findings of the present study can be used to approximate the impact of potential disease progression on QL by comparing patients with relatively benign AK to those having developed SCC and multiple diagnoses.
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Patient-reported health outcomes in patients with non-melanoma skin cancer and actinic keratosis: results from a large-scale observational study analysing effects of diagnoses and disease progression.
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