Reuse of malaria rapid diagnostic tests for amplicon deep sequencing to estimate Plasmodium falciparum transmission intensity in western Uganda.

Interestingly, we did observe a divergent effect of infection complexity on the risk of severe malaria among children <5 years of age, who had a relatively negligible risk of severe disease with a more complex infection (≥3 identified haplotypes), compared to adults and children ≥5 years of age, who had a clear trend ( p = 0.07) towards a reduced risk of severe disease with more complex infections.

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