No Overt Clinical Immunodeficiency Despite Immune Biological Abnormalities in Patients With Constitutional Mismatch Repair Deficiency.

Front Immunol · 2018 · PMC6036136 · PMID 30013564

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a clear trendno p-value reported

Still, we detected a clear trend of reduced CD38 hi IgM − plasmablasts (measured as a percent of B cells in 12 patients: normal in 3 patients, reduced in 7, absent in 2, and an increased in none) and a relative increase of CD21 low CD38 low (activated) B cells in 6 of 12 patients across all three genotypes analyzed (Table 3 ).

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