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Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC<sup>+</sup> CD4<sup>+</sup> cell levels: a surrogate marker candidate of HIV-induced intestinal damage.

J Int AIDS Soc · 2018 · PMC6038000 · PMID 29987877

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showed a trendno p-value reported
The animals showed a trend for sDPP4 increase at the end of the IL‐21 treatment (week 6 p.i) and a statistically significant increase at the following time point that was four weeks after IL‐21 administration (week 10 p.i, p < 0.01).

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