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Substitutions for arginine at position 780 in triple helical domain of the α1(I) chain alter folding of the type I procollagen molecule and cause osteogenesis imperfecta.

PLoS One · 2018 · PMC6039012 · PMID 29990383

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Western blot analysis ( Fig 8A ) provided evidence of increased EIF2α phosphorylation expected in cell stress, but this trend did not reach statistical significance.

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