Low-density lipoprotein (LDL)-dependent uptake of Gram-positive lipoteichoic acid and Gram-negative lipopolysaccharide occurs through LDL receptor.

Data obtained after Day 7 suggests that plasma PCSK9 concentrations continue to transiently increase and return to normal levels during the course of 14 days in ICU, however the Day 8 differences did not reach statistical significance due to low sample size at this time-point.

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